# The reading list

> Evermore Aesthetics reading shelf — The Evermore Aesthetics reading list: original collagen, skin-penetration and hair papers alongside GHK-Cu reviews.

**The source shelf**

Culture dishes, skin preparations and people appear in different places in this collection.

## A route through the collection

For the most contained experiment, begin with [collagen synthesis in human fibroblast cultures](https://pubmed.ncbi.nlm.nih.gov/3169264/). The [tissue-remodelling review](https://pubmed.ncbi.nlm.nih.gov/18644225/) then widens the subject to the proteins and signals involved in repair.

The [skin-regeneration review](https://pmc.ncbi.nlm.nih.gov/articles/PMC4508379/) and the [topical anti-wrinkle review](https://pmc.ncbi.nlm.nih.gov/articles/PMC11830136/) collect the cosmetic material. They are syntheses of other work. Reviews occupy their own shelf in my estimation, apart from a single experiment.

## Delivery and hair

The [human-skin penetration paper](https://pmc.ncbi.nlm.nih.gov/articles/PMC3016279/) follows copper in skin outside the body. The [human GHK combination hair trial](https://pmc.ncbi.nlm.nih.gov/articles/PMC4969472/) measures hair-count changes, while the [AHK-Cu follicle study](https://pubmed.ncbi.nlm.nih.gov/17703734/) concerns a related molecule in laboratory settings.

My affection for this collection lies in those changes of scale. The papers do more interesting work when they are allowed to remain distinct.

## References

[1] Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ https://pubmed.ncbi.nlm.nih.gov/3169264/
[2] The human tri-peptide GHK and tissue remodeling https://pubmed.ncbi.nlm.nih.gov/18644225/
[3] GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration https://pmc.ncbi.nlm.nih.gov/articles/PMC4508379/
[4] Topically applied GHK as an anti-wrinkle peptide: Advantages, problems and prospective https://pmc.ncbi.nlm.nih.gov/articles/PMC11830136/
[5] Human skin penetration of a copper tripeptide in vitro as a function of skin layer https://pmc.ncbi.nlm.nih.gov/articles/PMC3016279/
[6] Efficacy of a Complex of 5-Aminolevulinic Acid and Glycyl-Histidyl-Lysine Peptide on Hair Growth https://pmc.ncbi.nlm.nih.gov/articles/PMC4969472/
[7] The effect of tripeptide-copper complex on human hair growth in vitro https://pubmed.ncbi.nlm.nih.gov/17703734/

---

At Evermore Aesthetics I sift published research on skin and repair for an editorial archive, with no aesthetics business or medical advice behind the name.